Tunis is home to one the best museums in North Africa, The Bardo, which is housed in a beautiful palace filled with the treasures found at numerous ancient sites dotted around Tunisia. It's easy to get to, just jump on tram number 4. The local tourist offices have maps and are helpful, their employees speak fluent French and decent English.
While there are many hotels in Tunis, a light rail system makes it very easy to stay in the gorgeous, picturesque village of Sidi Bou Said on the coast, just 20 minutes away. En route are the ancient ruins of Carthage.
Getting around Tunis is easy by foot, light rail or taxis. Just make sure the taxis use their meters.
More about travel in Tunisia.